A Cre-LoxP-based approach for combinatorial chromosome rearrangements in human HAP1 cells
A Cre-LoxP-based approach for combinatorial chromosome rearrangements in human HAP1 cells
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Publisher
Dordrecht: Springer Netherlands
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Language
English
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Dordrecht: Springer Netherlands
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Contents
Alterations of human karyotype caused by chromosomal rearrangements are often associated with considerable phenotypic effects. Studying molecular mechanisms underlying these effects requires an efficient and scalable experimental model. Here, we propose a Cre-LoxP–based approach for the generation of combinatorial diversity of chromosomal rearrange...
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Full title
A Cre-LoxP-based approach for combinatorial chromosome rearrangements in human HAP1 cells
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TN_cdi_proquest_miscellaneous_2780079399
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2780079399
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ISSN
1573-6849,0967-3849
E-ISSN
1573-6849
DOI
10.1007/s10577-023-09719-7
