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Diagnostic value of MDM2 RNA in situ hybridization for low-grade osteosarcoma: Consistency compariso...

Diagnostic value of MDM2 RNA in situ hybridization for low-grade osteosarcoma: Consistency compariso...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2792511996

Diagnostic value of MDM2 RNA in situ hybridization for low-grade osteosarcoma: Consistency comparison of RNA in situ hybridization, fluorescence in situ hybridization, and immunohistochemistry

About this item

Full title

Diagnostic value of MDM2 RNA in situ hybridization for low-grade osteosarcoma: Consistency comparison of RNA in situ hybridization, fluorescence in situ hybridization, and immunohistochemistry

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Virchows Archiv : an international journal of pathology, 2023-06, Vol.482 (6), p.999-1010

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Detection of
MDM2
gene amplification via fluorescence in situ hybridization (FISH) and MDM2 overexpression by immunohistochemistry (IHC) have been utilized for the diagnosis of low-grade osteosarcoma (LGOS). The aim of this study was to evaluate the diagnostic value of
MDM2
RNA in situ hybridization (RNA-ISH) and compare this assay with...

Alternative Titles

Full title

Diagnostic value of MDM2 RNA in situ hybridization for low-grade osteosarcoma: Consistency comparison of RNA in situ hybridization, fluorescence in situ hybridization, and immunohistochemistry

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2792511996

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2792511996

Other Identifiers

ISSN

0945-6317

E-ISSN

1432-2307

DOI

10.1007/s00428-023-03530-9

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