Quantitative profiling of pseudouridylation landscape in the human transcriptome
Quantitative profiling of pseudouridylation landscape in the human transcriptome
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Author / Creator
Zhang, Meiling , Jiang, Zhe , Ma, Yichen , Liu, Wenqing , Zhuang, Yuan , Lu, Bo , Li, Kai , Peng, Jinying and Yi, Chengqi
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Pseudouridine (Ψ) is an abundant post-transcriptional RNA modification in ncRNA and mRNA. However, stoichiometric measurement of individual Ψ sites in human transcriptome remains unaddressed. Here we develop ‘PRAISE’, via selective chemical labeling of Ψ by bisulfite to induce nucleotide deletion signature during reverse transcription, to realize q...
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Full title
Quantitative profiling of pseudouridylation landscape in the human transcriptome
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Record Identifier
TN_cdi_proquest_miscellaneous_2793988423
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2793988423
Other Identifiers
ISSN
1552-4450
E-ISSN
1552-4469
DOI
10.1038/s41589-023-01304-7
