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Identification of HDAC4 as a potential therapeutic target and prognostic biomarker for ZFTA-fused ep...

Identification of HDAC4 as a potential therapeutic target and prognostic biomarker for ZFTA-fused ep...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2800146692

Identification of HDAC4 as a potential therapeutic target and prognostic biomarker for ZFTA-fused ependymomas

About this item

Full title

Identification of HDAC4 as a potential therapeutic target and prognostic biomarker for ZFTA-fused ependymomas

Publisher

New York: Nature Publishing Group US

Journal title

Cancer gene therapy, 2023-08, Vol.30 (8), p.1105-1113

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Members of the HDAC family are predictive biomarkers and regulate the tumorigenesis in several cancers. However, the role of these genes in the biology of intracranial ependymomas (EPNs) remains unexplored. Here, an analysis of eighteen HDACs genes in an EPN transcriptomic dataset, revealed significantly higher levels of
HDAC4
in supratentori...

Alternative Titles

Full title

Identification of HDAC4 as a potential therapeutic target and prognostic biomarker for ZFTA-fused ependymomas

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2800146692

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2800146692

Other Identifiers

ISSN

0929-1903

E-ISSN

1476-5500

DOI

10.1038/s41417-023-00616-z

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