EBF1–JAK2 inhibits the PAX5 function through physical interaction with PAX5 and kinase activity
EBF1–JAK2 inhibits the PAX5 function through physical interaction with PAX5 and kinase activity
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Author / Creator
Kojima, Yukino , Kawashima, Fumika , Yasuda, Takahiko , Odaira, Koya , Inagaki, Yuichiro , Yamada, Chiharu , Muraki, Ami , Noura, Mina , Okamoto, Shuichi , Tamura, Shogo , Iwamoto, Eisuke , Sanada, Masashi , Matsumura, Itaru , Miyazaki, Yasushi , Kojima, Tetsuhito , Kiyoi, Hitoshi , Tsuzuki, Shinobu and Hayakawa, Fumihiko
Publisher
Singapore: Springer Nature Singapore
Journal title
Language
English
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Publisher
Singapore: Springer Nature Singapore
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Scope and Contents
Contents
Gene aberrations of B-cell regulators and growth signal components such as the JAK–STAT pathway are frequently found in B-cell acute lymphoblastic leukemia (B-ALL). EBF1 is a B-cell regulator that regulates the expression of PAX5 and co-operates with PAX5 to regulate B-cell differentiation. Here, we analyzed the function of the fusion protein of EB...
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Full title
EBF1–JAK2 inhibits the PAX5 function through physical interaction with PAX5 and kinase activity
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Record Identifier
TN_cdi_proquest_miscellaneous_2810917067
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2810917067
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ISSN
0925-5710
E-ISSN
1865-3774
DOI
10.1007/s12185-023-03585-z
