Yersinia YopJ Acetylates and Inhibits Kinase Activation by Blocking Phosphorylation
Yersinia YopJ Acetylates and Inhibits Kinase Activation by Blocking Phosphorylation
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Washington, DC: American Association for the Advancement of Science
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Language
English
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Washington, DC: American Association for the Advancement of Science
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Contents
Yersinia species use a variety of type III effector proteins to target eukaryotic signaling systems. The effector Yop] inhibits mitogen-activated protein kinase (MAPK) and the nuclear factor κB (NFκB) signaling pathways used in innate immune response by preventing activation of the family of MAPK kinases (MAPKK). We show that Yop] acted as an acety...
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Full title
Yersinia YopJ Acetylates and Inhibits Kinase Activation by Blocking Phosphorylation
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TN_cdi_proquest_miscellaneous_28145955
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_28145955
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1126867
