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Safety and efficacy of valbenazine for the treatment of chorea associated with Huntington's disease...

Safety and efficacy of valbenazine for the treatment of chorea associated with Huntington's disease...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2816761676

Safety and efficacy of valbenazine for the treatment of chorea associated with Huntington's disease (KINECT-HD): a phase 3, randomised, double-blind, placebo-controlled trial

About this item

Full title

Safety and efficacy of valbenazine for the treatment of chorea associated with Huntington's disease (KINECT-HD): a phase 3, randomised, double-blind, placebo-controlled trial

Author / Creator

Furr Stimming, Erin , Claassen, Daniel O , Kayson, Elise , Goldstein, Jody , Mehanna, Raja , Zhang, Hui , Liang, Grace S , Haubenberger, Dietrich , Adams, Jamie , Beck, Christopher , Chen, Cheryl , Nance, Martha , Testa, Claudia , Huffman, Patricia , Chesire, Amy , Marshall, Frederick , Dayalu, Praveen , Stovall, Angela , Hall, Deborah , Hawkins, Jacob , Ginsburg, Letty , Moore, Henry , Mestre, Tiago , Thompson, Tanya , Connors, Natalie , Rosas, H. Diana , Daley, Allison , Kostyk, Sandra K. , Mitchell, Casey , Hellman, Amy , Houston, Sheryl , Buchanan, Danielle , McDonell, Katherine , Factor, Stewart A. , Sperin, Elaine , Hurt, Andrea , Wojcieszek, Joanne , Adurogbangba, Mike , Raymond, Lynn A. , Corey-Bloom, Jody , Snell, Chase , Blair, Courtney , Sung, Victor , Antonioli, Sophia , Fung, Jacqueline , Laganiere, Simon , Sierra, Luis , Mallonee, William M. , Suter, Greg , Bega, Danny , Brown, Zsa Zsa , Elmer, Lawrence , Vollmar, Nancy , del Castillo, Debra , Lin, Yi-Han , Andrzejewski, Kelly , Weigel, Patricia , Hawkins, Trevor , Kirby, Kendra , Retzik-Stahr, Cimmaron , Seeberger, Lauren , Dhall, Rohit , Rassmann, Anja , Luxmore, McKenzie , Scott, Burton , Bulica, Bisena , Boyd, James , Chan, Katherine , McFarland, Nikolaus , Rizer, Kyle , Conlon, Patricia , Suski, Valerie , Rodriguez-Porcel, Federico , Wilson, Sandra , Farrell, Christine , Hunter, David , Houghton, David , Seoane, Sarah , Gibbons, Clare , Rizek, Philippe , Kuprewicz, Robin , Lo, Steven , Cuturic, Miroslav , Segro, Vicki , Greenly, Kate , Revilla, Fredy , Urrea-Mendoza, Enrique , Black, Kevin J. , Davis, Thomas , Stover, Natividad , Duker, Andrew , Van Gerpen, Jay , Hedera, Peter , Ondo, William , Anderson, Karen , Bradley, Stephen , Cheung, Ken , Frank, Samuel and Huntington Study Group KINECT-HD Collaborators

Publisher

England: Elsevier Ltd

Journal title

Lancet neurology, 2023-06, Vol.22 (6), p.494-504

Language

English

Formats

Publication information

Publisher

England: Elsevier Ltd

More information

Scope and Contents

Contents

Valbenazine is a highly selective vesicular monoamine transporter 2 (VMAT2) inhibitor approved for treatment of tardive dyskinesia. To address the ongoing need for improved symptomatic treatments for individuals with Huntington's disease, valbenazine was evaluated for the treatment of chorea associated with Huntington's disease.
KINECT-HD (NCT04...

Alternative Titles

Full title

Safety and efficacy of valbenazine for the treatment of chorea associated with Huntington's disease (KINECT-HD): a phase 3, randomised, double-blind, placebo-controlled trial

Authors, Artists and Contributors

Author / Creator

Furr Stimming, Erin
Claassen, Daniel O
Kayson, Elise
Goldstein, Jody
Mehanna, Raja
Zhang, Hui
Liang, Grace S
Haubenberger, Dietrich
Adams, Jamie
Beck, Christopher
Chen, Cheryl
Nance, Martha
Testa, Claudia
Huffman, Patricia
Chesire, Amy
Marshall, Frederick
Dayalu, Praveen
Stovall, Angela
Hall, Deborah
Hawkins, Jacob
Ginsburg, Letty
Moore, Henry
Mestre, Tiago
Thompson, Tanya
Connors, Natalie
Rosas, H. Diana
Daley, Allison
Kostyk, Sandra K.
Mitchell, Casey
Hellman, Amy
Houston, Sheryl
Buchanan, Danielle
McDonell, Katherine
Factor, Stewart A.
Sperin, Elaine
Hurt, Andrea
Wojcieszek, Joanne
Adurogbangba, Mike
Raymond, Lynn A.
Corey-Bloom, Jody
Snell, Chase
Blair, Courtney
Sung, Victor
Antonioli, Sophia
Fung, Jacqueline
Laganiere, Simon
Sierra, Luis
Mallonee, William M.
Suter, Greg
Bega, Danny
Brown, Zsa Zsa
Elmer, Lawrence
Vollmar, Nancy
del Castillo, Debra
Lin, Yi-Han
Andrzejewski, Kelly
Weigel, Patricia
Hawkins, Trevor
Kirby, Kendra
Retzik-Stahr, Cimmaron
Seeberger, Lauren
Dhall, Rohit
Rassmann, Anja
Luxmore, McKenzie
Scott, Burton
Bulica, Bisena
Boyd, James
Chan, Katherine
McFarland, Nikolaus
Rizer, Kyle
Conlon, Patricia
Suski, Valerie
Rodriguez-Porcel, Federico
Wilson, Sandra
Farrell, Christine
Hunter, David
Houghton, David
Seoane, Sarah
Gibbons, Clare
Rizek, Philippe
Kuprewicz, Robin
Lo, Steven
Cuturic, Miroslav
Segro, Vicki
Greenly, Kate
Revilla, Fredy
Urrea-Mendoza, Enrique
Black, Kevin J.
Davis, Thomas
Stover, Natividad
Duker, Andrew
Van Gerpen, Jay
Hedera, Peter
Ondo, William
Anderson, Karen
Bradley, Stephen
Cheung, Ken
Frank, Samuel
Huntington Study Group KINECT-HD Collaborators

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2816761676

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2816761676

Other Identifiers

ISSN

1474-4422

E-ISSN

1474-4465

DOI

10.1016/S1474-4422(23)00127-8

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