α-Ketoglutarate-dependent Enzymes in Breast Cancer and Therapeutic Implications
α-Ketoglutarate-dependent Enzymes in Breast Cancer and Therapeutic Implications
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US: Oxford University Press
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English
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US: Oxford University Press
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Abstract
α-Ketoglutarate (αKG)-dependent dioxygenases are a superfamily of enzymes that require oxygen, reduced iron, and αKG for their catalytic functions. Therefore, they have the potential to sense the availabilities of oxygen, iron, and specific metabolites, including αKG and its structurally related metabolites. These enzymes play essential...
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Full title
α-Ketoglutarate-dependent Enzymes in Breast Cancer and Therapeutic Implications
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TN_cdi_proquest_miscellaneous_2816767929
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2816767929
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ISSN
1945-7170,0013-7227
E-ISSN
1945-7170
DOI
10.1210/endocr/bqad080
