Proteolytic rewiring of mitochondria by LONP1 directs cell identity switching of adipocytes
Proteolytic rewiring of mitochondria by LONP1 directs cell identity switching of adipocytes
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Fu, Tingting , Sun, Wanping , Xue, Jiachen , Zhou, Zheng , Wang, Wen , Guo, Qiqi , Chen, Xinyi , Zhou, Danxia , Xu, Zhisheng , Liu, Lin , Xiao, Liwei , Mao, Yan , Yang, Likun , Yin, Yujing , Zhang, Xue-Na , Wan, Qiangyou , Lu, Bin , Chen, Yuncong , Zhu, Min-Sheng , Scherer, Philipp E. , Fang, Lei , Piao, Hai-Long , Shao, Mengle and Gan, Zhenji
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Mitochondrial proteases are emerging as key regulators of mitochondrial plasticity and acting as both protein quality surveillance and regulatory enzymes by performing highly regulated proteolytic reactions. However, it remains unclear whether the regulated mitochondrial proteolysis is mechanistically linked to cell identity switching. Here we repo...
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Proteolytic rewiring of mitochondria by LONP1 directs cell identity switching of adipocytes
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TN_cdi_proquest_miscellaneous_2818053566
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2818053566
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ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/s41556-023-01155-3