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GPR116 promotes ferroptosis in sepsis-induced liver injury by suppressing system Xc–/GSH/GPX4

GPR116 promotes ferroptosis in sepsis-induced liver injury by suppressing system Xc–/GSH/GPX4

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2822377370

GPR116 promotes ferroptosis in sepsis-induced liver injury by suppressing system Xc–/GSH/GPX4

About this item

Full title

GPR116 promotes ferroptosis in sepsis-induced liver injury by suppressing system Xc–/GSH/GPX4

Publisher

Dordrecht: Springer Netherlands

Journal title

Cell biology and toxicology, 2023-12, Vol.39 (6), p.3015-3030

Language

English

Formats

Publication information

Publisher

Dordrecht: Springer Netherlands

More information

Scope and Contents

Contents

The disease sepsis is caused by an infection that damages organs. Liver injury, with ferroptosis playing a key role, is an early sign of sepsis. G protein-coupled receptor 116 (GPR116) is essential in the maintenance of functional homeostasis in various systems of the body and has been proven to play a protective role in septic lung injury. However...

Alternative Titles

Full title

GPR116 promotes ferroptosis in sepsis-induced liver injury by suppressing system Xc–/GSH/GPX4

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2822377370

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2822377370

Other Identifiers

ISSN

0742-2091,1573-6822

E-ISSN

1573-6822

DOI

10.1007/s10565-023-09815-8

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