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Tankyrase: a promising therapeutic target with pleiotropic action

Tankyrase: a promising therapeutic target with pleiotropic action

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2827921857

Tankyrase: a promising therapeutic target with pleiotropic action

About this item

Full title

Tankyrase: a promising therapeutic target with pleiotropic action

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Naunyn-Schmiedeberg's archives of pharmacology, 2023-12, Vol.396 (12), p.3363-3374

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Tankyrase 1 (TNKS1) and tankyrase 2 (TNKS2) enzymes belong to the poly (ADP-ribose) polymerase (PARP) family participates in process of poly-ADP-ribosylation of different target proteins which leads to ubiquitin-mediated proteasomal degradation. Tankyrases are also involved in the pathophysiology of many diseases, especially cancer. Their functions...

Alternative Titles

Full title

Tankyrase: a promising therapeutic target with pleiotropic action

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2827921857

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2827921857

Other Identifiers

ISSN

0028-1298

E-ISSN

1432-1912

DOI

10.1007/s00210-023-02576-5

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