Comprehensive spatiotemporal mapping of single-cell lineages in developing mouse brain by CRISPR-bas...
Comprehensive spatiotemporal mapping of single-cell lineages in developing mouse brain by CRISPR-based barcoding
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Author / Creator
Xie, Lianshun , Liu, Hengxin , You, Zhiwen , Wang, Luyue , Li, Yiwen , Zhang, Xinyue , Ji, Xiaoshan , He, Hui , Yuan, Tingli , Zheng, Wenping , Wu, Ziyan , Xiong, Man , Wei, Wu and Chen, Yuejun
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
A fundamental interest in developmental neuroscience lies in the ability to map the complete single-cell lineages within the brain. To this end, we developed a CRISPR editing-based lineage-specific tracing (CREST) method for clonal tracing in Cre mice. We then used two complementary strategies based on CREST to map single-cell lineages in developin...
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Full title
Comprehensive spatiotemporal mapping of single-cell lineages in developing mouse brain by CRISPR-based barcoding
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Record Identifier
TN_cdi_proquest_miscellaneous_2839248114
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2839248114
Other Identifiers
ISSN
1548-7091
E-ISSN
1548-7105
DOI
10.1038/s41592-023-01947-3
