A method to map single-cell lineages in the mouse brain by CRISPR-based barcoding
A method to map single-cell lineages in the mouse brain by CRISPR-based barcoding
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Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
We developed CREST (CRISPR editing-based lineage-specific tracing) to enable high-throughput mapping of single-cell lineages in any Cre lineage of interest in mice. In addition, we delineated a comprehensive lineage landscape of the developing mouse ventral midbrain, revealing novel differentiation trajectories and molecular programs underlying neu...
Alternative Titles
Full title
A method to map single-cell lineages in the mouse brain by CRISPR-based barcoding
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Record Identifier
TN_cdi_proquest_miscellaneous_2839248146
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2839248146
Other Identifiers
ISSN
1548-7091
E-ISSN
1548-7105
DOI
10.1038/s41592-023-01948-2
