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Ultrafast nLight indicators for sensitive and specific in vivo imaging of norepinephrine

Ultrafast nLight indicators for sensitive and specific in vivo imaging of norepinephrine

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2841020095

Ultrafast nLight indicators for sensitive and specific in vivo imaging of norepinephrine

About this item

Full title

Ultrafast nLight indicators for sensitive and specific in vivo imaging of norepinephrine

Publisher

New York: Nature Publishing Group US

Journal title

Nature methods, 2023-09, Vol.20 (9), p.1289-1290

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

We developed, characterized and validated nLight sensors, a new family of genetically encoded green and red fluorescent norepinephrine indicators based on an alpha-1 adrenergic receptor. nLight probes can detect norepinephrine in living animals with superior sensitivity, ligand specificity and temporal resolution as compared with previous tools.

Alternative Titles

Full title

Ultrafast nLight indicators for sensitive and specific in vivo imaging of norepinephrine

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2841020095

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2841020095

Other Identifiers

ISSN

1548-7091

E-ISSN

1548-7105

DOI

10.1038/s41592-023-01960-6

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