LONRF2 is a protein quality control ubiquitin ligase whose deficiency causes late-onset neurological...
LONRF2 is a protein quality control ubiquitin ligase whose deficiency causes late-onset neurological deficits
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Author / Creator
Li, Dan , Johmura, Yoshikazu , Morimoto, Satoru , Doi, Miyuki , Nakanishi, Keiko , Ozawa, Manabu , Tsunekawa, Yuji , Inoue-Yamauchi, Akane , Naruse, Hiroya , Matsukawa, Takashi , Takeshita, Yukio , Suzuki, Naoki , Aoki, Masashi , Nishiyama, Ayumi , Zeng, Xin , Konishi, Chieko , Suzuki, Narumi , Nishiyama, Atsuya , Harris, Alexander Stephen , Morita, Mariko , Yamaguchi, Kiyoshi , Furukawa, Yoichi , Nakai, Kenta , Tsuji, Shoji , Yamazaki, Satoshi , Yamanashi, Yuji , Shimada, Shoichi , Okada, Takashi , Okano, Hideyuki , Toda, Tatsushi and Nakanishi, Makoto
Publisher
United States: Nature Publishing Group
Journal title
Language
English
Formats
Publication information
Publisher
United States: Nature Publishing Group
Subjects
More information
Scope and Contents
Contents
Protein misfolding is a major factor of neurodegenerative diseases. Post-mitotic neurons are highly susceptible to protein aggregates that are not diluted by mitosis. Therefore, post-mitotic cells may have a specific protein quality control system. Here, we show that LONRF2 is a bona fide protein quality control ubiquitin ligase induced in post-mit...
Alternative Titles
Full title
LONRF2 is a protein quality control ubiquitin ligase whose deficiency causes late-onset neurological deficits
Authors, Artists and Contributors
Author / Creator
Johmura, Yoshikazu
Morimoto, Satoru
Doi, Miyuki
Nakanishi, Keiko
Ozawa, Manabu
Tsunekawa, Yuji
Inoue-Yamauchi, Akane
Naruse, Hiroya
Matsukawa, Takashi
Takeshita, Yukio
Suzuki, Naoki
Aoki, Masashi
Nishiyama, Ayumi
Zeng, Xin
Konishi, Chieko
Suzuki, Narumi
Nishiyama, Atsuya
Harris, Alexander Stephen
Morita, Mariko
Yamaguchi, Kiyoshi
Furukawa, Yoichi
Nakai, Kenta
Tsuji, Shoji
Yamazaki, Satoshi
Yamanashi, Yuji
Shimada, Shoichi
Okada, Takashi
Okano, Hideyuki
Toda, Tatsushi
Nakanishi, Makoto
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2841020379
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2841020379
Other Identifiers
ISSN
2662-8465
E-ISSN
2662-8465
DOI
10.1038/s43587-023-00464-4
