A fast chemical reprogramming system promotes cell identity transition through a diapause-like state
A fast chemical reprogramming system promotes cell identity transition through a diapause-like state
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Author / Creator
Chen, Xi , Lu, Yunkun , Wang, Leyun , Ma, Xiaojie , Pu, Jiaqi , Lin, Lianyu , Deng, Qian , Li, Yuhan , Wang, Weiyun , Jin, Yan , Hu, Zhensheng , Zhou, Ziyu , Chen, Guo , Jiang, Liling , Wang, Hao , Zhao, Xiaoyang , He, Xiangwei , Fu, Junfen , Russ, Holger A. , Li, Wei and Zhu, Saiyong
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Cellular reprogramming by only small molecules holds enormous potentials for regenerative medicine. However, chemical reprogramming remains a slow process and labour intensive, hindering its broad applications and the investigation of underlying molecular mechanisms. Here, through screening of over 21,000 conditions, we develop a fast chemical repr...
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Full title
A fast chemical reprogramming system promotes cell identity transition through a diapause-like state
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TN_cdi_proquest_miscellaneous_2847746344
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2847746344
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ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/s41556-023-01193-x