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Unsupervised removal of systematic background noise from droplet-based single-cell experiments using...

Unsupervised removal of systematic background noise from droplet-based single-cell experiments using...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2847746393

Unsupervised removal of systematic background noise from droplet-based single-cell experiments using CellBender

About this item

Full title

Unsupervised removal of systematic background noise from droplet-based single-cell experiments using CellBender

Publisher

New York: Nature Publishing Group US

Journal title

Nature methods, 2023-09, Vol.20 (9), p.1323-1335

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Droplet-based single-cell assays, including single-cell RNA sequencing (scRNA-seq), single-nucleus RNA sequencing (snRNA-seq) and cellular indexing of transcriptomes and epitopes by sequencing (CITE-seq), generate considerable background noise counts, the hallmark of which is nonzero counts in cell-free droplets and off-target gene expression in un...

Alternative Titles

Full title

Unsupervised removal of systematic background noise from droplet-based single-cell experiments using CellBender

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2847746393

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2847746393

Other Identifiers

ISSN

1548-7091

E-ISSN

1548-7105

DOI

10.1038/s41592-023-01943-7

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