Log in to save to my catalogue

Bacterial production and biophysical characterization of a hard-to-fold scFv against myeloid leukemi...

Bacterial production and biophysical characterization of a hard-to-fold scFv against myeloid leukemi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2849897389

Bacterial production and biophysical characterization of a hard-to-fold scFv against myeloid leukemia cell surface marker, IL-1RAP

About this item

Full title

Bacterial production and biophysical characterization of a hard-to-fold scFv against myeloid leukemia cell surface marker, IL-1RAP

Publisher

Dordrecht: Springer Netherlands

Journal title

Molecular biology reports, 2023-02, Vol.50 (2), p.1191-1202

Language

English

Formats

Publication information

Publisher

Dordrecht: Springer Netherlands

More information

Scope and Contents

Contents

Background
Interleukin-1 receptor accessory protein (IL-1RAP) is one of the most promising therapeutic targets proposed for myeloid leukemia. Antibodies (Abs) specific to IL-1RAP could be valuable tools for targeted therapy of this lethal malignancy. This study is about the preparation of a difficult-to-produce single-chain variable fragment (sc...

Alternative Titles

Full title

Bacterial production and biophysical characterization of a hard-to-fold scFv against myeloid leukemia cell surface marker, IL-1RAP

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2849897389

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2849897389

Other Identifiers

ISSN

0301-4851,1573-4978

E-ISSN

1573-4978

DOI

10.1007/s11033-022-07972-3

How to access this item