YAP governs cellular adaptation to perturbation of glutamine metabolism by regulating ATF4-mediated...
YAP governs cellular adaptation to perturbation of glutamine metabolism by regulating ATF4-mediated stress response
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Proliferating cells have metabolic dependence on glutamine to fuel anabolic pathways and to refill the mitochondrial carbon pool. The Hippo pathway is essential for coordinating cell survival and growth with nutrient availability, but no molecular connection to glutamine deprivation has been reported. Here, we identify a non-canonical role of YAP,...
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YAP governs cellular adaptation to perturbation of glutamine metabolism by regulating ATF4-mediated stress response
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TN_cdi_proquest_miscellaneous_2853940713
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2853940713
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-023-02811-6
