Multiplexed transcriptomic profiling of the fate of human CAR T cells in vivo via genetic barcoding...
Multiplexed transcriptomic profiling of the fate of human CAR T cells in vivo via genetic barcoding with shielded small nucleotides
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The design of chimeric antigen receptor (CAR) T cells would benefit from knowledge of the fate of the cells in vivo. This requires the permanent labelling of CAR T cell products and their pooling in the same microenvironment. Here, we report a cell-barcoding method for the multiplexed longitudinal profiling of cells in vivo using single-cell RNA se...
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Full title
Multiplexed transcriptomic profiling of the fate of human CAR T cells in vivo via genetic barcoding with shielded small nucleotides
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TN_cdi_proquest_miscellaneous_2860401235
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2860401235
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ISSN
2157-846X
E-ISSN
2157-846X
DOI
10.1038/s41551-023-01085-3
