Molecular mechanisms of SARS-CoV-2 resistance to nirmatrelvir
Molecular mechanisms of SARS-CoV-2 resistance to nirmatrelvir
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Author / Creator
Duan, Yinkai , Zhou, Hao , Liu, Xiang , Iketani, Sho , Lin, Mengmeng , Zhang, Xiaoyu , Bian, Qucheng , Wang, Haofeng , Sun, Haoran , Hong, Seo Jung , Culbertson, Bruce , Mohri, Hiroshi , Luck, Maria I. , Zhu, Yan , Liu, Xiaoce , Lu, Yuchi , Yang, Xiuna , Yang, Kailin , Sabo, Yosef , Chavez, Alejandro , Goff, Stephen P. , Rao, Zihe , Ho, David D. and Yang, Haitao
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Nirmatrelvir is a specific antiviral drug that targets the main protease (M
pro
) of SARS-CoV-2 and has been approved to treat COVID-19
1
,
2
. As an RNA virus characterized by high mutation rates, whether SARS-CoV-2 will develop resistance to nirmatrelvir is a question of concern. Our previous studies have shown that several muta...
Alternative Titles
Full title
Molecular mechanisms of SARS-CoV-2 resistance to nirmatrelvir
Authors, Artists and Contributors
Author / Creator
Zhou, Hao
Liu, Xiang
Iketani, Sho
Lin, Mengmeng
Zhang, Xiaoyu
Bian, Qucheng
Wang, Haofeng
Sun, Haoran
Hong, Seo Jung
Culbertson, Bruce
Mohri, Hiroshi
Luck, Maria I.
Zhu, Yan
Liu, Xiaoce
Lu, Yuchi
Yang, Xiuna
Yang, Kailin
Sabo, Yosef
Chavez, Alejandro
Goff, Stephen P.
Rao, Zihe
Ho, David D.
Yang, Haitao
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2864158241
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2864158241
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-023-06609-0
