Discovery of the Next Generation of Non-peptidomimetic Neurolysin Activators with High Blood-Brain B...
Discovery of the Next Generation of Non-peptidomimetic Neurolysin Activators with High Blood-Brain Barrier Permeability: a Pharmacokinetics Study in Healthy and Stroke Animals
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Publisher
New York: Springer US
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Language
English
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Publisher
New York: Springer US
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Purpose
There is growing interest in seeking pharmacological activation of neurolysin (Nln) for stroke treatment. Discovery of central nervous system drugs remains challenging due to the protection of the blood-brain barrier (BBB). The previously reported peptidomimetic Nln activators display unsatisfactory BBB penetration. Herein, we investigat...
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Full title
Discovery of the Next Generation of Non-peptidomimetic Neurolysin Activators with High Blood-Brain Barrier Permeability: a Pharmacokinetics Study in Healthy and Stroke Animals
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TN_cdi_proquest_miscellaneous_2877380026
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2877380026
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ISSN
0724-8741
E-ISSN
1573-904X
DOI
10.1007/s11095-023-03619-5
