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Comprehensive In silico analysis of chaperones identifies CRYAB and P4HA2 as potential therapeutic t...

Comprehensive In silico analysis of chaperones identifies CRYAB and P4HA2 as potential therapeutic t...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2878292752

Comprehensive In silico analysis of chaperones identifies CRYAB and P4HA2 as potential therapeutic targets and their small-molecule inhibitors for the treatment of cholangiocarcinoma

About this item

Full title

Comprehensive In silico analysis of chaperones identifies CRYAB and P4HA2 as potential therapeutic targets and their small-molecule inhibitors for the treatment of cholangiocarcinoma

Publisher

United States: Elsevier Ltd

Journal title

Computers in biology and medicine, 2023-11, Vol.166, p.107572-107572, Article 107572

Language

English

Formats

Publication information

Publisher

United States: Elsevier Ltd

More information

Scope and Contents

Contents

AbstractCholangiocarcinoma (CCA) is a subtype of liver cancer with increasing incidence, poor prognosis, and limited treatment modalities. It is, therefore, imperative to identify novel therapeutic targets for better management of the disease. Chaperones are known to be significant regulators of carcinogenesis, however, their role in CCA remains un...

Alternative Titles

Full title

Comprehensive In silico analysis of chaperones identifies CRYAB and P4HA2 as potential therapeutic targets and their small-molecule inhibitors for the treatment of cholangiocarcinoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2878292752

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2878292752

Other Identifiers

ISSN

0010-4825,1879-0534

E-ISSN

1879-0534

DOI

10.1016/j.compbiomed.2023.107572

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