Molecular mechanism of glutaminase activation through filamentation and the role of filaments in mit...
Molecular mechanism of glutaminase activation through filamentation and the role of filaments in mitophagy protection
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Author / Creator
Adamoski, Douglas , Dias, Marilia Meira , Quesñay, Jose Edwin Neciosup , Yang, Zhengyi , Zagoriy, Ievgeniia , Steyer, Anna M. , Rodrigues, Camila Tanimoto , da Silva Bastos, Alliny Cristiny , da Silva, Bianca Novaes , Costa, Renna Karoline Eloi , de Abreu, Flávia Mayumi Odahara , Islam, Zeyaul , Cassago, Alexandre , van Heel, Marin Gerard , Consonni, Sílvio Roberto , Mattei, Simone , Mahamid, Julia , Portugal, Rodrigo Villares , Ambrosio, Andre Luis Berteli and Dias, Sandra Martha Gomes
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Glutaminase (GLS), which deaminates glutamine to form glutamate, is a mitochondrial tetrameric protein complex. Although inorganic phosphate (Pi) is known to promote GLS filamentation and activation, the molecular basis of this mechanism is unknown. Here we aimed to determine the molecular mechanism of Pi-induced mouse GLS filamentation and its imp...
Alternative Titles
Full title
Molecular mechanism of glutaminase activation through filamentation and the role of filaments in mitophagy protection
Authors, Artists and Contributors
Author / Creator
Dias, Marilia Meira
Quesñay, Jose Edwin Neciosup
Yang, Zhengyi
Zagoriy, Ievgeniia
Steyer, Anna M.
Rodrigues, Camila Tanimoto
da Silva Bastos, Alliny Cristiny
da Silva, Bianca Novaes
Costa, Renna Karoline Eloi
de Abreu, Flávia Mayumi Odahara
Islam, Zeyaul
Cassago, Alexandre
van Heel, Marin Gerard
Consonni, Sílvio Roberto
Mattei, Simone
Mahamid, Julia
Portugal, Rodrigo Villares
Ambrosio, Andre Luis Berteli
Dias, Sandra Martha Gomes
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2880103559
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2880103559
Other Identifiers
ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/s41594-023-01118-0
