A Novel Milli-fluidic Liver Tissue Chip with Continuous Recirculation for Predictive Pharmacokinetic...
A Novel Milli-fluidic Liver Tissue Chip with Continuous Recirculation for Predictive Pharmacokinetics Applications
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Publisher
Cham: Springer International Publishing
Journal title
Language
English
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Publication information
Publisher
Cham: Springer International Publishing
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Scope and Contents
Contents
A crucial step in lead selection during drug development is accurate estimation and optimization of hepatic clearance using
in vitro
methods. However, current methods are limited by factors such as lack of physiological relevance, short culture/incubation times that are not consistent with drug exposure patterns in patients, use of drug absor...
Alternative Titles
Full title
A Novel Milli-fluidic Liver Tissue Chip with Continuous Recirculation for Predictive Pharmacokinetics Applications
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Record Identifier
TN_cdi_proquest_miscellaneous_2883577564
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2883577564
Other Identifiers
ISSN
1550-7416
E-ISSN
1550-7416
DOI
10.1208/s12248-023-00870-x
