Genetics and epidemiology of mutational barcode-defined clonal hematopoiesis
Genetics and epidemiology of mutational barcode-defined clonal hematopoiesis
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Author / Creator
Stacey, Simon N. , Zink, Florian , Halldorsson, Gisli H. , Stefansdottir, Lilja , Gudjonsson, Sigurjon A. , Einarsson, Gudmundur , Hjörleifsson, Grimur , Eiriksdottir, Thjodbjorg , Helgadottir, Anna , Björnsdottir, Gyda , Thorgeirsson, Thorgeir E. , Olafsdottir, Thorunn A. , Jonsdottir, Ingileif , Gretarsdottir, Solveig , Tragante, Vinicius , Magnusson, Magnus K. , Jonsson, Hakon , Gudmundsson, Julius , Olafsson, Sigurgeir , Holm, Hilma , Gudbjartsson, Daniel F. , Sulem, Patrick , Helgason, Agnar , Thorsteinsdottir, Unnur , Tryggvadottir, Laufey , Rafnar, Thorunn , Melsted, Pall , Ulfarsson, Magnus Ö. , Vidarsson, Brynjar , Thorleifsson, Gudmar and Stefansson, Kari
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
Clonal hematopoiesis (CH) arises when a substantial proportion of mature blood cells is derived from a single hematopoietic stem cell lineage. Using whole-genome sequencing of 45,510 Icelandic and 130,709 UK Biobank participants combined with a mutational barcode method, we identified 16,306 people with CH. Prevalence approaches 50% in elderly part...
Alternative Titles
Full title
Genetics and epidemiology of mutational barcode-defined clonal hematopoiesis
Authors, Artists and Contributors
Author / Creator
Zink, Florian
Halldorsson, Gisli H.
Stefansdottir, Lilja
Gudjonsson, Sigurjon A.
Einarsson, Gudmundur
Hjörleifsson, Grimur
Eiriksdottir, Thjodbjorg
Helgadottir, Anna
Björnsdottir, Gyda
Thorgeirsson, Thorgeir E.
Olafsdottir, Thorunn A.
Jonsdottir, Ingileif
Gretarsdottir, Solveig
Tragante, Vinicius
Magnusson, Magnus K.
Jonsson, Hakon
Gudmundsson, Julius
Olafsson, Sigurgeir
Holm, Hilma
Gudbjartsson, Daniel F.
Sulem, Patrick
Helgason, Agnar
Thorsteinsdottir, Unnur
Tryggvadottir, Laufey
Rafnar, Thorunn
Melsted, Pall
Ulfarsson, Magnus Ö.
Vidarsson, Brynjar
Thorleifsson, Gudmar
Stefansson, Kari
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2886936798
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2886936798
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/s41588-023-01555-z
