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Regulatory T cell-derived IL-1Ra suppresses the innate response to respiratory viral infection

Regulatory T cell-derived IL-1Ra suppresses the innate response to respiratory viral infection

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2889240702

Regulatory T cell-derived IL-1Ra suppresses the innate response to respiratory viral infection

About this item

Full title

Regulatory T cell-derived IL-1Ra suppresses the innate response to respiratory viral infection

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2023-12, Vol.24 (12), p.2091-2107

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Regulatory T (T
reg
) cell modulation of adaptive immunity and tissue homeostasis is well described; however, less is known about T
reg
cell-mediated regulation of the innate immune response. Here we show that deletion of ST2, the receptor for interleukin (IL)-33, on T
reg
cells increased granulocyte influx into the lung and incre...

Alternative Titles

Full title

Regulatory T cell-derived IL-1Ra suppresses the innate response to respiratory viral infection

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2889240702

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2889240702

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/s41590-023-01655-2

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