The regional pattern of age-related synaptic loss in the human brain differs from gray matter volume...
The regional pattern of age-related synaptic loss in the human brain differs from gray matter volume loss: in vivo PET measurement with [11C]UCB-J
About this item
Full title
Author / Creator
Toyonaga, Takuya , Khattar, Nikkita , Wu, Yanjun , Lu, Yihuan , Naganawa, Mika , Gallezot, Jean-Dominique , Matuskey, David , Mecca, Adam P. , Pittman, Brian , Dias, Mark , Nabulsi, Nabeel B. , Finnema, Sjoerd J. , Chen, Ming-Kai , Arnsten, Amy , Radhakrishnan, Rajiv , Skosnik, Patrick D. , D’Souza, Deepak Cyril , Esterlis, Irina , Huang, Yiyun , van Dyck, Christopher H. and Carson, Richard E.
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
Purpose
Aging is a major societal concern due to age-related functional losses. Synapses are crucial components of neural circuits, and synaptic density could be a sensitive biomarker to evaluate brain function. [
11
C]UCB-J is a positron emission tomography (PET) ligand targeting synaptic vesicle glycoprotein 2A (SV2A), which can be used...
Alternative Titles
Full title
The regional pattern of age-related synaptic loss in the human brain differs from gray matter volume loss: in vivo PET measurement with [11C]UCB-J
Authors, Artists and Contributors
Author / Creator
Khattar, Nikkita
Wu, Yanjun
Lu, Yihuan
Naganawa, Mika
Gallezot, Jean-Dominique
Matuskey, David
Mecca, Adam P.
Pittman, Brian
Dias, Mark
Nabulsi, Nabeel B.
Finnema, Sjoerd J.
Chen, Ming-Kai
Arnsten, Amy
Radhakrishnan, Rajiv
Skosnik, Patrick D.
D’Souza, Deepak Cyril
Esterlis, Irina
Huang, Yiyun
van Dyck, Christopher H.
Carson, Richard E.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2889588132
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2889588132
Other Identifiers
ISSN
1619-7070
E-ISSN
1619-7089
DOI
10.1007/s00259-023-06487-8
