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Longitudinal course of neurofilament light chain levels in amyotrophic lateral sclerosis—insights fr...

Longitudinal course of neurofilament light chain levels in amyotrophic lateral sclerosis—insights fr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2891754903

Longitudinal course of neurofilament light chain levels in amyotrophic lateral sclerosis—insights from a completed randomized controlled trial with rasagiline

About this item

Full title

Longitudinal course of neurofilament light chain levels in amyotrophic lateral sclerosis—insights from a completed randomized controlled trial with rasagiline

Publisher

England: John Wiley & Sons, Inc

Journal title

European journal of neurology, 2024-03, Vol.31 (3), p.e16154-n/a

Language

English

Formats

Publication information

Publisher

England: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Background and purpose
Rasagiline might be disease modifying in patients with amyotrophic lateral sclerosis (ALS). The aim was to evaluate the effect of rasagiline 2 mg/day on neurofilament light chain (NfL), a prognostic biomarker in ALS.
Methods
In 65 patients with ALS randomized in a 3:1 ratio to rasagiline 2 mg/day (n = 48) or placebo...

Alternative Titles

Full title

Longitudinal course of neurofilament light chain levels in amyotrophic lateral sclerosis—insights from a completed randomized controlled trial with rasagiline

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2891754903

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2891754903

Other Identifiers

ISSN

1351-5101,1468-1331

E-ISSN

1468-1331

DOI

10.1111/ene.16154

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