Alkyl Derivatives of Perylene Photosensitizing Antivirals: Towards Understanding the Influence of Li...
Alkyl Derivatives of Perylene Photosensitizing Antivirals: Towards Understanding the Influence of Lipophilicity
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Author / Creator
Mikhnovets, Igor E. , Holoubek, Jiří , Panina, Irina S. , Kotouček, Jan , Gvozdev, Daniil A. , Chumakov, Stepan P. , Krasilnikov, Maxim S. , Zhitlov, Mikhail Y. , Gulyak, Evgeny L. , Chistov, Alexey A. , Nikitin, Timofei D. , Korshun, Vladimir A. , Efremov, Roman G. , Alferova, Vera A. , Růžek, Daniel , Eyer, Luděk and Ustinov, Alexey V.
Publisher
Basel: MDPI AG
Journal title
Language
English
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Publication information
Publisher
Basel: MDPI AG
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More information
Scope and Contents
Contents
Amphipathic perylene derivatives are broad-spectrum antivirals against enveloped viruses that act as fusion inhibitors in a light-dependent manner. The compounds target the lipid bilayer of the viral envelope using the lipophilic perylene moiety and photogenerating singlet oxygen, thereby causing damage to unsaturated lipids. Previous studies show...
Alternative Titles
Full title
Alkyl Derivatives of Perylene Photosensitizing Antivirals: Towards Understanding the Influence of Lipophilicity
Authors, Artists and Contributors
Author / Creator
Holoubek, Jiří
Panina, Irina S.
Kotouček, Jan
Gvozdev, Daniil A.
Chumakov, Stepan P.
Krasilnikov, Maxim S.
Zhitlov, Mikhail Y.
Gulyak, Evgeny L.
Chistov, Alexey A.
Nikitin, Timofei D.
Korshun, Vladimir A.
Efremov, Roman G.
Alferova, Vera A.
Růžek, Daniel
Eyer, Luděk
Ustinov, Alexey V.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2893843007
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2893843007
Other Identifiers
ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms242216483