A second-generation M1-polarized CAR macrophage with antitumor efficacy
A second-generation M1-polarized CAR macrophage with antitumor efficacy
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Author / Creator
Lei, Anhua , Yu, Hua , Lu, Shan , Lu, Hengxing , Ding, Xizhong , Tan, Tianyu , Zhang, Hailing , Zhu, Mengmeng , Tian, Lin , Wang, Xudong , Su, Siyu , Xue, Dixuan , Zhang, Shaolong , Zhao, Wei , Chen, Yuge , Xie, Wanrun , Zhang, Li , Zhu, Yuqing , Zhao, Jing , Jiang, Wenhong , Church, George , Chan, Francis Ka-Ming , Gao, Zhihua and Zhang, Jin
Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Chimeric antigen receptor (CAR) T cell therapies have successfully treated hematological malignancies. Macrophages have also gained attention as an immunotherapy owing to their immunomodulatory capacity and ability to infiltrate solid tumors and phagocytize tumor cells. The first-generation CD3ζ-based CAR-macrophages could phagocytose tumor cells i...
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Full title
A second-generation M1-polarized CAR macrophage with antitumor efficacy
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Record Identifier
TN_cdi_proquest_miscellaneous_2894725097
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2894725097
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/s41590-023-01687-8
