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RAB7 deficiency impairs pulmonary artery endothelial function and promotes pulmonary hypertension

RAB7 deficiency impairs pulmonary artery endothelial function and promotes pulmonary hypertension

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2895261794

RAB7 deficiency impairs pulmonary artery endothelial function and promotes pulmonary hypertension

About this item

Full title

RAB7 deficiency impairs pulmonary artery endothelial function and promotes pulmonary hypertension

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2024-02, Vol.134 (3), p.1-14

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Pulmonary arterial hypertension (PAH) is a devastating and progressive disease with limited treatment options. Endothelial dysfunction plays a central role in the development and progression of PAH, yet the underlying mechanisms are incompletely understood. The endosome-lysosome system is important to maintain cellular health, and the small GTPase...

Alternative Titles

Full title

RAB7 deficiency impairs pulmonary artery endothelial function and promotes pulmonary hypertension

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2895261794

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2895261794

Other Identifiers

ISSN

1558-8238,0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI169441

How to access this item