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A global view of aging and Alzheimer’s pathogenesis-associated cell population dynamics and molecula...

A global view of aging and Alzheimer’s pathogenesis-associated cell population dynamics and molecula...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2896809105

A global view of aging and Alzheimer’s pathogenesis-associated cell population dynamics and molecular signatures in human and mouse brains

About this item

Full title

A global view of aging and Alzheimer’s pathogenesis-associated cell population dynamics and molecular signatures in human and mouse brains

Publisher

New York: Nature Publishing Group US

Journal title

Nature genetics, 2023-12, Vol.55 (12), p.2104-2116

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Conventional methods fall short in unraveling the dynamics of rare cell types related to aging and diseases. Here we introduce EasySci, an advanced single-cell combinatorial indexing strategy for exploring age-dependent cellular dynamics in the mammalian brain. Profiling approximately 1.5 million single-cell transcriptomes and 400,000 chromatin acc...

Alternative Titles

Full title

A global view of aging and Alzheimer’s pathogenesis-associated cell population dynamics and molecular signatures in human and mouse brains

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2896809105

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2896809105

Other Identifiers

ISSN

1061-4036,1546-1718

E-ISSN

1546-1718

DOI

10.1038/s41588-023-01572-y

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