Single-cell sequencing reveals Hippo signaling as a driver of fibrosis in hidradenitis suppurativa
Single-cell sequencing reveals Hippo signaling as a driver of fibrosis in hidradenitis suppurativa
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Author / Creator
van Straalen, Kelsey R. , Ma, Feiyang , Tsou, Pei-Suen , Plazyo, Olesya , Gharaee-Kermani, Mehrnaz , Calbet, Marta , Xing, Xianying , Sarkar, Mrinal K. , Uppala, Ranjitha , Harms, Paul W. , Wasikowski, Rachael , Nahlawi, Lina , Nakamura, Mio , Eshaq, Milad , Wang, Cong , Dobry, Craig , Kozlow, Jeffrey H. , Cherry-Bukowiec, Jill , Brodie, William D. , Wolk, Kerstin , Uluçkan, Özge , Mattichak, Megan N. , Pellegrini, Matteo , Modlin, Robert L. , Maverakis, Emanual , Sabat, Robert , Kahlenberg, J. Michelle , Billi, Allison C. , Tsoi, Lam C. and Gudjonsson, Johann E.
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
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Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Hidradenitis suppurativa (HS) is a chronic inflammatory disease characterized by abscesses, nodules, dissecting/draining tunnels, and extensive fibrosis. Here, we integrate single-cell RNA sequencing, spatial transcriptomics, and immunostaining to provide an unprecedented view of the pathogenesis of chronic HS, characterizing the main cellular play...
Alternative Titles
Full title
Single-cell sequencing reveals Hippo signaling as a driver of fibrosis in hidradenitis suppurativa
Authors, Artists and Contributors
Author / Creator
Ma, Feiyang
Tsou, Pei-Suen
Plazyo, Olesya
Gharaee-Kermani, Mehrnaz
Calbet, Marta
Xing, Xianying
Sarkar, Mrinal K.
Uppala, Ranjitha
Harms, Paul W.
Wasikowski, Rachael
Nahlawi, Lina
Nakamura, Mio
Eshaq, Milad
Wang, Cong
Dobry, Craig
Kozlow, Jeffrey H.
Cherry-Bukowiec, Jill
Brodie, William D.
Wolk, Kerstin
Uluçkan, Özge
Mattichak, Megan N.
Pellegrini, Matteo
Modlin, Robert L.
Maverakis, Emanual
Sabat, Robert
Kahlenberg, J. Michelle
Billi, Allison C.
Tsoi, Lam C.
Gudjonsson, Johann E.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2898954453
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2898954453
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI169225
