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High Filamin a Expression in Adrenocortical Carcinomas Is Associated with a Favourable Tumour Behavi...

High Filamin a Expression in Adrenocortical Carcinomas Is Associated with a Favourable Tumour Behavi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2902963348

High Filamin a Expression in Adrenocortical Carcinomas Is Associated with a Favourable Tumour Behaviour: A European Multicentric Study

About this item

Full title

High Filamin a Expression in Adrenocortical Carcinomas Is Associated with a Favourable Tumour Behaviour: A European Multicentric Study

Publisher

Switzerland: MDPI AG

Journal title

International journal of molecular sciences, 2023-12, Vol.24 (23), p.16573

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

The insulin-like growth factor 2 (IGF2) promotes cell growth by overactivating the IGF system in an autocrine loop in adrenocortical carcinomas (ACCs). The cytoskeleton protein filamin A (FLNA) acts as a repressor of IGF2 mitogenic signalling in ACC cells. The aims of this study were to test FLNA expression by immunohistochemistry in 119 ACCs and 2...

Alternative Titles

Full title

High Filamin a Expression in Adrenocortical Carcinomas Is Associated with a Favourable Tumour Behaviour: A European Multicentric Study

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2902963348

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2902963348

Other Identifiers

ISSN

1422-0067,1661-6596

E-ISSN

1422-0067

DOI

10.3390/ijms242316573

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