Efficacy and safety of aldosterone synthase inhibition with and without empagliflozin for chronic ki...
Efficacy and safety of aldosterone synthase inhibition with and without empagliflozin for chronic kidney disease: a randomised, controlled, phase 2 trial
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Author / Creator
ASi in CKD group , Tuttle, Katherine R , Hauske, Sibylle J , Canziani, Maria Eugenia , Caramori, Maria Luiza , Cherney, David , Cronin, Lisa , Heerspink, Hiddo J L , Hugo, Christian , Nangaku, Masaomi , Rotter, Ricardo Correa , Silva, Arnold , Shah, Shimoli V , Sun, Zhichao , Urbach, Dorothea , de Zeeuw, Dick , Rossing, Peter , SZETO, Cheuk Chun , Echeverri, Diego , Martin, Edouard , Yee, Ming Li , Wah, William , Wang, Ray , Chacko, Bobby , Swaminathan, Shriram , MacIsaac, Richard , Hashimura, Hikaru , Ward, Glenn , De Vusser, Katrien , Claes, Kathleen , Kuypers, Dirk , Meijers, Björn , Van Craenenbroeck, Amaryllis , Hilbrands, Robert , Debroye, Corinne , Wissing, Karl Martin , Jadoul, Michel , Demoulin, Nathalie , Treille De Grandsaigne, Serge , Beklevic, Ishak , Marcoux, Diane , Liénart, Fabienne , Daper, Claude , De Brouckere, Véronique , Heureux, Mercédès , Felicio, Joao , Felicio, Karem Mileo , Leite, Daniella , Melo, Franciane , Queiroz, Natercia , Souza, Ana Carolina , Vieira, Jocyelle , Franco, Roberto , Mendes, Adriana , Picolli, Giovana , Canani, Luis Henrique , Sartori, Carla , Valenti, Adriana , Eliaschewitz, Freddy , Bona, Renata , Franco, Denise , Ludovico Costa de Castro, Denise , Magalhaes, Vanessa , Oliveira, Marcelo , Sampaio, Célia Regina , Visconti, Guilherme , Halpern, Bruno , Nihei, Camila , Pessoa, Bruna , Seraphim, Carlos , Santos, Daniel , Brito, Claudia , Douverny, Joao , Colella, Marina , Gazeta, Cristina , Vercia, Monique , Watanabe, Renato , Temelkova, Theodora , Kjurkchiev, Dimo , Statkova, Silviya , Popov, Iliya , Radeva, Radosveta , Arabadzhiev, Lachezar , Binova, Mariya , Bosilkov, Aleksandar , Koleva-Stoicheva, Neli , Ivanov, Ivaylo , Ivanova, Zornitsa , Kotseva, Viktoria , Spasov, Petar , Tsvetkov, Ivaylo , Jolly, Shivinder , Bailey, Gordon , Ye, Zhiming , Niu, Jianying , Li, Hongmei , Wu, Qing , Liao, Bing , Hao, Chuanming , Lai, Lingyun and Xu, Yunyu
Publisher
England: Elsevier Limited
Journal title
Language
English
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Publication information
Publisher
England: Elsevier Limited
Subjects
More information
Scope and Contents
Contents
Excess aldosterone accelerates chronic kidney disease progression. This phase 2 clinical trial assessed BI 690517, an aldosterone synthase inhibitor, for efficacy, safety, and dose selection.
This was a multinational, randomised, controlled, phase 2 trial. People aged 18 years or older with an estimated glomerular filtration rate (eGFR) of 30 to...
Alternative Titles
Full title
Efficacy and safety of aldosterone synthase inhibition with and without empagliflozin for chronic kidney disease: a randomised, controlled, phase 2 trial
Authors, Artists and Contributors
Author / Creator
Tuttle, Katherine R
Hauske, Sibylle J
Canziani, Maria Eugenia
Caramori, Maria Luiza
Cherney, David
Cronin, Lisa
Heerspink, Hiddo J L
Hugo, Christian
Nangaku, Masaomi
Rotter, Ricardo Correa
Silva, Arnold
Shah, Shimoli V
Sun, Zhichao
Urbach, Dorothea
de Zeeuw, Dick
Rossing, Peter
SZETO, Cheuk Chun
Echeverri, Diego
Martin, Edouard
Yee, Ming Li
Wah, William
Wang, Ray
Chacko, Bobby
Swaminathan, Shriram
MacIsaac, Richard
Hashimura, Hikaru
Ward, Glenn
De Vusser, Katrien
Claes, Kathleen
Kuypers, Dirk
Meijers, Björn
Van Craenenbroeck, Amaryllis
Hilbrands, Robert
Debroye, Corinne
Wissing, Karl Martin
Jadoul, Michel
Demoulin, Nathalie
Treille De Grandsaigne, Serge
Beklevic, Ishak
Marcoux, Diane
Liénart, Fabienne
Daper, Claude
De Brouckere, Véronique
Heureux, Mercédès
Felicio, Joao
Felicio, Karem Mileo
Leite, Daniella
Melo, Franciane
Queiroz, Natercia
Souza, Ana Carolina
Vieira, Jocyelle
Franco, Roberto
Mendes, Adriana
Picolli, Giovana
Canani, Luis Henrique
Sartori, Carla
Valenti, Adriana
Eliaschewitz, Freddy
Bona, Renata
Franco, Denise
Ludovico Costa de Castro, Denise
Magalhaes, Vanessa
Oliveira, Marcelo
Sampaio, Célia Regina
Visconti, Guilherme
Halpern, Bruno
Nihei, Camila
Pessoa, Bruna
Seraphim, Carlos
Santos, Daniel
Brito, Claudia
Douverny, Joao
Colella, Marina
Gazeta, Cristina
Vercia, Monique
Watanabe, Renato
Temelkova, Theodora
Kjurkchiev, Dimo
Statkova, Silviya
Popov, Iliya
Radeva, Radosveta
Arabadzhiev, Lachezar
Binova, Mariya
Bosilkov, Aleksandar
Koleva-Stoicheva, Neli
Ivanov, Ivaylo
Ivanova, Zornitsa
Kotseva, Viktoria
Spasov, Petar
Tsvetkov, Ivaylo
Jolly, Shivinder
Bailey, Gordon
Ye, Zhiming
Niu, Jianying
Li, Hongmei
Wu, Qing
Liao, Bing
Hao, Chuanming
Lai, Lingyun
Xu, Yunyu
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2903859389
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2903859389
Other Identifiers
ISSN
0140-6736,1474-547X
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(23)02408-X
