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MGMT promoter methylation in 1p19q-intact gliomas

MGMT promoter methylation in 1p19q-intact gliomas

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2904156061

MGMT promoter methylation in 1p19q-intact gliomas

About this item

Full title

MGMT promoter methylation in 1p19q-intact gliomas

Publisher

New York: Springer US

Journal title

Journal of neuro-oncology, 2024-01, Vol.166 (1), p.73-78

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Objective
Standard-of-care for 1p19q-intact anaplastic gliomas is defined by the international randomized phase III CATNON trial, which found an overall survival (OS) benefit for adjuvant temozolomide (TMZ) when added to radiotherapy. Paradoxically, TMZ did not appear to benefit patients with IDH-wildtype gliomas, regardless of
MGMT
promot...

Alternative Titles

Full title

MGMT promoter methylation in 1p19q-intact gliomas

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2904156061

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2904156061

Other Identifiers

ISSN

0167-594X

E-ISSN

1573-7373

DOI

10.1007/s11060-023-04515-z

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