Safety and efficacy of platelet glycoprotein VI inhibition in acute ischaemic stroke (ACTIMIS): a ra...
Safety and efficacy of platelet glycoprotein VI inhibition in acute ischaemic stroke (ACTIMIS): a randomised, double-blind, placebo-controlled, phase 1b/2a trial
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Author / Creator
Mazighi, Mikaël , Köhrmann, Martin , Lemmens, Robin , Lyrer, Philippe A , Molina, Carlos A , Richard, Sébastien , Toni, Danilo , Plétan, Yannick , Sari, Anouar , Meilhoc, Adeline , Jandrot-Perrus, Martine , Binay, Sophie , Avenard, Gilles , Comenducci, Andrea , Grouin, Jean-Marie , Grotta, James C , Albucher, Jean François , Alonso, Angelika , Berrouschot, Jörg , Cordonnier, Charlotte , de Raedt, Sylvie , Desfontaines, Philippe , Doche, Emilie , Hemelsoet, Dimitri , Macian-Montoro, Francisco , Masjuan, Jaime , Obadia, Michael , Peeters, André , Pelz, Johann , Reiner, Peggy , Segura, Tomas , Serena, Joaquin , Sibon, Igor , Tembl, Jose I. , Vannier, Stéphane , Zuber, Mathieu and ACTIMIS Study Group
Publisher
England: Elsevier Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: Elsevier Ltd
Subjects
More information
Scope and Contents
Contents
Antagonists of glycoprotein VI-triggered platelet activation used in combination with recanalisation therapies are a promising therapeutic approach in acute ischaemic stroke. Glenzocimab is an antibody fragment that inhibits the action of platelet glycoprotein VI. We aimed to determine and assess the safety and efficacy of the optimal dose of glenz...
Alternative Titles
Full title
Safety and efficacy of platelet glycoprotein VI inhibition in acute ischaemic stroke (ACTIMIS): a randomised, double-blind, placebo-controlled, phase 1b/2a trial
Authors, Artists and Contributors
Author / Creator
Köhrmann, Martin
Lemmens, Robin
Lyrer, Philippe A
Molina, Carlos A
Richard, Sébastien
Toni, Danilo
Plétan, Yannick
Sari, Anouar
Meilhoc, Adeline
Jandrot-Perrus, Martine
Binay, Sophie
Avenard, Gilles
Comenducci, Andrea
Grouin, Jean-Marie
Grotta, James C
Albucher, Jean François
Alonso, Angelika
Berrouschot, Jörg
Cordonnier, Charlotte
de Raedt, Sylvie
Desfontaines, Philippe
Doche, Emilie
Hemelsoet, Dimitri
Macian-Montoro, Francisco
Masjuan, Jaime
Obadia, Michael
Peeters, André
Pelz, Johann
Reiner, Peggy
Segura, Tomas
Serena, Joaquin
Sibon, Igor
Tembl, Jose I.
Vannier, Stéphane
Zuber, Mathieu
ACTIMIS Study Group
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2918514463
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2918514463
Other Identifiers
ISSN
1474-4422,1474-4465
E-ISSN
1474-4465
DOI
10.1016/S1474-4422(23)00427-1
