Adenine base editor‐based correction of the cardiac pathogenic Lmna c.1621C > T mutation in murine h...
Adenine base editor‐based correction of the cardiac pathogenic Lmna c.1621C > T mutation in murine hearts
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Author / Creator
Yang, Luzi , Liu, Zhanzhao , Sun, Jinhuan , Chen, Zhan , Gao, Fei and Guo, Yuxuan
Publisher
England: John Wiley & Sons, Inc
Journal title
Language
English
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Publisher
England: John Wiley & Sons, Inc
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Scope and Contents
Contents
Base editors are emerging as powerful tools to correct single‐nucleotide variants and treat genetic diseases. In particular, the adenine base editors (ABEs) exhibit robust and accurate adenine‐to‐guanidine editing capacity and have entered the clinical stage for cardiovascular therapy. Despite the tremendous progress using ABEs to treat heart disea...
Alternative Titles
Full title
Adenine base editor‐based correction of the cardiac pathogenic Lmna c.1621C > T mutation in murine hearts
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Author / Creator
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Record Identifier
TN_cdi_proquest_miscellaneous_2924996446
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2924996446
Other Identifiers
ISSN
1582-1838,1582-4934
E-ISSN
1582-4934
DOI
10.1111/jcmm.18145