Convolutional Neural Networks Guided Raman Spectroscopy as a Process Analytical Technology (PAT) Too...
Convolutional Neural Networks Guided Raman Spectroscopy as a Process Analytical Technology (PAT) Tool for Monitoring and Simultaneous Prediction of Monoclonal Antibody Charge Variants
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New York: Springer US
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English
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New York: Springer US
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Background
Charge related heterogeneities of monoclonal antibody (mAb) based therapeutic products are increasingly being considered as a critical quality attribute (CQA). They are typically estimated using analytical cation exchange chromatography (CEX), which is time consuming and not suitable for real time control. Raman spectroscopy coupled w...
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Full title
Convolutional Neural Networks Guided Raman Spectroscopy as a Process Analytical Technology (PAT) Tool for Monitoring and Simultaneous Prediction of Monoclonal Antibody Charge Variants
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TN_cdi_proquest_miscellaneous_2928244788
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2928244788
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ISSN
0724-8741
E-ISSN
1573-904X
DOI
10.1007/s11095-024-03663-9