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The role of TSC1 and TSC2 proteins in neuronal axons

The role of TSC1 and TSC2 proteins in neuronal axons

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2929027563

The role of TSC1 and TSC2 proteins in neuronal axons

About this item

Full title

The role of TSC1 and TSC2 proteins in neuronal axons

Publisher

London: Nature Publishing Group UK

Journal title

Molecular psychiatry, 2024-04, Vol.29 (4), p.1165-1178

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Tuberous Sclerosis Complex 1 and 2 proteins, TSC1 and TSC2 respectively, participate in a multiprotein complex with a crucial role for the proper development and function of the nervous system. This complex primarily acts as an inhibitor of the mechanistic target of rapamycin (mTOR) kinase, and mutations in either TSC1 or TSC2 cause a neurodevelopm...

Alternative Titles

Full title

The role of TSC1 and TSC2 proteins in neuronal axons

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2929027563

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2929027563

Other Identifiers

ISSN

1359-4184,1476-5578

E-ISSN

1476-5578

DOI

10.1038/s41380-023-02402-7

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