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Knockdown of the Shwachman-Diamond syndrome gene, SBDS, induces galectin-1 expression and impairs ce...

Knockdown of the Shwachman-Diamond syndrome gene, SBDS, induces galectin-1 expression and impairs ce...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2929060127

Knockdown of the Shwachman-Diamond syndrome gene, SBDS, induces galectin-1 expression and impairs cell growth

About this item

Full title

Knockdown of the Shwachman-Diamond syndrome gene, SBDS, induces galectin-1 expression and impairs cell growth

Publisher

Singapore: Springer Nature Singapore

Journal title

International journal of hematology, 2024-04, Vol.119 (4), p.383-391

Language

English

Formats

Publication information

Publisher

Singapore: Springer Nature Singapore

More information

Scope and Contents

Contents

Shwachman-Diamond syndrome (SDS) is an autosomal recessive disorder characterized by exocrine pancreatic insufficiency and bone marrow failure. The depletion of SBDS protein by RNA interference has been shown to cause inhibition of cell proliferation in several cell lines. However, the precise mechanism by which the loss of SBDS leads to inhibition...

Alternative Titles

Full title

Knockdown of the Shwachman-Diamond syndrome gene, SBDS, induces galectin-1 expression and impairs cell growth

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2929060127

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2929060127

Other Identifiers

ISSN

0925-5710,1865-3774

E-ISSN

1865-3774

DOI

10.1007/s12185-024-03709-z

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