Soluble NKG2DLs Are Elevated in Breast Cancer Patients and Associate with Disease Outcome
Soluble NKG2DLs Are Elevated in Breast Cancer Patients and Associate with Disease Outcome
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Author / Creator
Seller, Anna , Tegeler, Christian M , Mauermann, Jonas , Schreiber, Tatjana , Hagelstein, Ilona , Liebel, Kai , Koch, André , Heitmann, Jonas S , Greiner, Sarah M , Hayn, Clara , Dannehl, Dominik , Engler, Tobias , Hartkopf, Andreas D , Hahn, Markus , Brucker, Sara Y , Salih, Helmut R and Märklin, Melanie
Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
Ligands of the natural killer group 2D (NKG2DL) family are expressed on malignant cells and are usually absent from healthy tissues. Recognition of NKG2DLs such as MICA/B and ULBP1-3 by the activating immunoreceptor NKG2D, expressed by NK and cytotoxic T cells, stimulates anti-tumor immunity in breast cancer. Upregulation of membrane-bound NKG2DLs...
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Full title
Soluble NKG2DLs Are Elevated in Breast Cancer Patients and Associate with Disease Outcome
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TN_cdi_proquest_miscellaneous_3038435956
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3038435956
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ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms25074126
