Targeting Group 3 Medulloblastoma by the Anti-PRUNE-1 and Anti-LSD1/KDM1A Epigenetic Molecules
Targeting Group 3 Medulloblastoma by the Anti-PRUNE-1 and Anti-LSD1/KDM1A Epigenetic Molecules
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Author / Creator
Bibbò, Francesca , Asadzadeh, Fatemeh , Boccia, Angelo , Sorice, Carmen , Bianco, Orazio , Saccà, Carmen Daniela , Majello, Barbara , Donofrio, Vittoria , Bifano, Delfina , De Martino, Lucia , Quaglietta, Lucia , Cristofano, Adriana , Covelli, Eugenio Maria , Cinalli, Giuseppe , Ferrucci, Veronica , De Antonellis, Pasqualino and Zollo, Massimo
Publisher
Switzerland: MDPI AG
Journal title
Language
English
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Publisher
Switzerland: MDPI AG
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Scope and Contents
Contents
Medulloblastoma (MB) is a highly malignant childhood brain tumor. Group 3 MB (Gr3 MB) is considered to have the most metastatic potential, and tailored therapies for Gr3 MB are currently lacking. Gr3 MB is driven by PRUNE-1 amplification or overexpression. In this paper, we found that PRUNE-1 was transcriptionally regulated by lysine demethylase LS...
Alternative Titles
Full title
Targeting Group 3 Medulloblastoma by the Anti-PRUNE-1 and Anti-LSD1/KDM1A Epigenetic Molecules
Authors, Artists and Contributors
Author / Creator
Asadzadeh, Fatemeh
Boccia, Angelo
Sorice, Carmen
Bianco, Orazio
Saccà, Carmen Daniela
Majello, Barbara
Donofrio, Vittoria
Bifano, Delfina
De Martino, Lucia
Quaglietta, Lucia
Cristofano, Adriana
Covelli, Eugenio Maria
Cinalli, Giuseppe
Ferrucci, Veronica
De Antonellis, Pasqualino
Zollo, Massimo
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_3038436072
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3038436072
Other Identifiers
ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms25073917
