Intranasal immunization with the recombinant measles virus encoding the spike protein of SARS-CoV-2...
Intranasal immunization with the recombinant measles virus encoding the spike protein of SARS-CoV-2 confers protective immunity against COVID-19 in hamsters
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Author / Creator
Park, Sang-In , Park, Sohyun , Lee, Kunse , Kwak, Hye Won , Kim, Yong Kwan , Park, Hyeong-Jun , Bang, Yoo-Jin , Kim, Jae-Yong , Kim, Daegeun , Seo, Ki-Weon , Lee, Su Jeen , Kim, Hun , Kim, Yeonhwa , Kim, Do-Hyung , Park, Hyo-Jung , Jung, Seo-Yeon , Ga, Eulhae , Hwang, Jaehyun , Na, Woonsung , Hong, So-Hee , Lee, Sang-Myeong and Nam, Jae-Hwan
Publisher
Netherlands: Elsevier Ltd
Journal title
Language
English
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Publication information
Publisher
Netherlands: Elsevier Ltd
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Scope and Contents
Contents
Highlights•We studied the measles virus platform and nasal injection routes against COVID-19. •Hamsters received recombinant measles viruses expressing SARS-CoV-2 S protein. •Intranasal injection exhibited superior performance over intramuscular injection. •Intranasal immunization improves SARS-CoV-2 clearance in the respiratory tract.
Alternative Titles
Full title
Intranasal immunization with the recombinant measles virus encoding the spike protein of SARS-CoV-2 confers protective immunity against COVID-19 in hamsters
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Author / Creator
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Record Identifier
TN_cdi_proquest_miscellaneous_3040440891
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3040440891
Other Identifiers
ISSN
0264-410X
E-ISSN
1873-2518
DOI
10.1016/j.vaccine.2023.12.011
