Androgen receptor splice variants drive castration-resistant prostate cancer metastasis by activatin...
Androgen receptor splice variants drive castration-resistant prostate cancer metastasis by activating distinct transcriptional programs
About this item
Full title
Author / Creator
Han, Dong , Labaf, Maryam , Zhao, Yawei , Owiredu, Jude , Zhang, Songqi , Patel, Krishna , Venkataramani, Kavita , Steinfeld, Jocelyn S. , Han, Wanting , Li, Muqing , Liu, Mingyu , Wang, Zifeng , Besschetnova, Anna , Patalano, Susan , Mulhearn, Michaela J. , Macoska, Jill A. , Yuan, Xin , Balk, Steven P. , Nelson, Peter S. , Plymate, Stephen R. , Gao, Shuai , Siegfried, Kellee R. , Liu, Ruihua , Stangis, Mary M. , Foxa, Gabrielle , Czernik, Piotr J. , Williams, Bart O. , Zarringhalam, Kourosh , Li, Xiaohong and Cai, Changmeng
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
One critical mechanism through which prostate cancer (PCa) adapts to treatments targeting androgen receptor (AR) signaling is the emergence of ligand-binding domain-truncated and constitutively active AR splice variants, particularly AR-V7. While AR-V7 has been intensively studied, its ability to activate distinct biological functions compared with...
Alternative Titles
Full title
Androgen receptor splice variants drive castration-resistant prostate cancer metastasis by activating distinct transcriptional programs
Authors, Artists and Contributors
Author / Creator
Labaf, Maryam
Zhao, Yawei
Owiredu, Jude
Zhang, Songqi
Patel, Krishna
Venkataramani, Kavita
Steinfeld, Jocelyn S.
Han, Wanting
Li, Muqing
Liu, Mingyu
Wang, Zifeng
Besschetnova, Anna
Patalano, Susan
Mulhearn, Michaela J.
Macoska, Jill A.
Yuan, Xin
Balk, Steven P.
Nelson, Peter S.
Plymate, Stephen R.
Gao, Shuai
Siegfried, Kellee R.
Liu, Ruihua
Stangis, Mary M.
Foxa, Gabrielle
Czernik, Piotr J.
Williams, Bart O.
Zarringhalam, Kourosh
Li, Xiaohong
Cai, Changmeng
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_3049716444
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3049716444
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI168649
