Single-cell transcriptomic analyses reveal distinct immune cell contributions to epithelial barrier...
Single-cell transcriptomic analyses reveal distinct immune cell contributions to epithelial barrier dysfunction in checkpoint inhibitor colitis
About this item
Full title
Author / Creator
Thomas, Molly Fisher , Slowikowski, Kamil , Manakongtreecheep, Kasidet , Sen, Pritha , Samanta, Nandini , Tantivit, Jessica , Nasrallah, Mazen , Zubiri, Leyre , Smith, Neal P. , Tirard, Alice , Ramesh, Swetha , Arnold, Benjamin Y. , Nieman, Linda T. , Chen, Jonathan H. , Eisenhaure, Thomas , Pelka, Karin , Song, Yuhui , Xu, Katherine H. , Jorgji, Vjola , Pinto, Christopher J. , Sharova, Tatyana , Glasser, Rachel , Chan, PuiYee , Sullivan, Ryan J. , Khalili, Hamed , Juric, Dejan , Boland, Genevieve M. , Dougan, Michael , Hacohen, Nir , Li, Bo , Reynolds, Kerry L. and Villani, Alexandra-Chloé
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Immune checkpoint inhibitor (ICI) therapy has revolutionized oncology, but treatments are limited by immune-related adverse events, including checkpoint inhibitor colitis (irColitis). Little is understood about the pathogenic mechanisms driving irColitis, which does not readily occur in model organisms, such as mice. To define molecular drivers of...
Alternative Titles
Full title
Single-cell transcriptomic analyses reveal distinct immune cell contributions to epithelial barrier dysfunction in checkpoint inhibitor colitis
Authors, Artists and Contributors
Author / Creator
Slowikowski, Kamil
Manakongtreecheep, Kasidet
Sen, Pritha
Samanta, Nandini
Tantivit, Jessica
Nasrallah, Mazen
Zubiri, Leyre
Smith, Neal P.
Tirard, Alice
Ramesh, Swetha
Arnold, Benjamin Y.
Nieman, Linda T.
Chen, Jonathan H.
Eisenhaure, Thomas
Pelka, Karin
Song, Yuhui
Xu, Katherine H.
Jorgji, Vjola
Pinto, Christopher J.
Sharova, Tatyana
Glasser, Rachel
Chan, PuiYee
Sullivan, Ryan J.
Khalili, Hamed
Juric, Dejan
Boland, Genevieve M.
Dougan, Michael
Hacohen, Nir
Li, Bo
Reynolds, Kerry L.
Villani, Alexandra-Chloé
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_3053971788
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3053971788
Other Identifiers
ISSN
1078-8956,1546-170X
E-ISSN
1546-170X
DOI
10.1038/s41591-024-02895-x
