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Pancreatic β-Cell Identity Change through the Lens of Single-Cell Omics Research

Pancreatic β-Cell Identity Change through the Lens of Single-Cell Omics Research

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3053976977

Pancreatic β-Cell Identity Change through the Lens of Single-Cell Omics Research

About this item

Full title

Pancreatic β-Cell Identity Change through the Lens of Single-Cell Omics Research

Publisher

Switzerland: MDPI AG

Journal title

International journal of molecular sciences, 2024-05, Vol.25 (9), p.4720

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

The main hallmark in the development of both type 1 and type 2 diabetes is a decline in functional β-cell mass. This decline is predominantly attributed to β-cell death, although recent findings suggest that the loss of β-cell identity may also contribute to β-cell dysfunction. This phenomenon is characterized by a reduced expression of key markers...

Alternative Titles

Full title

Pancreatic β-Cell Identity Change through the Lens of Single-Cell Omics Research

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_3053976977

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3053976977

Other Identifiers

ISSN

1422-0067,1661-6596

E-ISSN

1422-0067

DOI

10.3390/ijms25094720

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