Aficamten for Symptomatic Obstructive Hypertrophic Cardiomyopathy
Aficamten for Symptomatic Obstructive Hypertrophic Cardiomyopathy
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Author / Creator
SEQUOIA-HCM Investigators , Maron, Martin S. , Masri, Ahmad , Nassif, Michael E. , Barriales-Villa, Roberto , Arad, Michael , Cardim, Nuno , Choudhury, Lubna , Claggett, Brian , Coats, Caroline J. , Düngen, Hans-Dirk , Garcia-Pavia, Pablo , Hagège, Albert A. , Januzzi, James L. , Lee, Matthew M.Y. , Lewis, Gregory D. , Ma, Chang-Sheng , Michels, Michelle , Olivotto, Iacopo , Oreziak, Artur , Owens, Anjali T. , Spertus, John A. , Solomon, Scott D. , Tfelt-Hansen, Jacob , van Sinttruije, Marion , Veselka, Josef , Watkins, Hugh , Jacoby, Daniel L. , Heitner, Stephen B. , Kupfer, Stuart , Malik, Fady I. , Meng, Lisa , Wohltman, Amy and Abraham, Theodore P.
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
One of the major determinants of exercise intolerance and limiting symptoms among patients with obstructive hypertrophic cardiomyopathy (HCM) is an elevated intracardiac pressure resulting from left ventricular outflow tract obstruction. Aficamten is an oral selective cardiac myosin inhibitor that reduces left ventricular outflow tract gradients by...
Alternative Titles
Full title
Aficamten for Symptomatic Obstructive Hypertrophic Cardiomyopathy
Authors, Artists and Contributors
Author / Creator
Maron, Martin S.
Masri, Ahmad
Nassif, Michael E.
Barriales-Villa, Roberto
Arad, Michael
Cardim, Nuno
Choudhury, Lubna
Claggett, Brian
Coats, Caroline J.
Düngen, Hans-Dirk
Garcia-Pavia, Pablo
Hagège, Albert A.
Januzzi, James L.
Lee, Matthew M.Y.
Lewis, Gregory D.
Ma, Chang-Sheng
Michels, Michelle
Olivotto, Iacopo
Oreziak, Artur
Owens, Anjali T.
Spertus, John A.
Solomon, Scott D.
Tfelt-Hansen, Jacob
van Sinttruije, Marion
Veselka, Josef
Watkins, Hugh
Jacoby, Daniel L.
Heitner, Stephen B.
Kupfer, Stuart
Malik, Fady I.
Meng, Lisa
Wohltman, Amy
Abraham, Theodore P.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_3054431439
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3054431439
Other Identifiers
ISSN
0028-4793,1533-4406
E-ISSN
1533-4406
DOI
10.1056/NEJMoa2401424
