Efficacy and Safety of Donidalorsen for Hereditary Angioedema
Efficacy and Safety of Donidalorsen for Hereditary Angioedema
About this item
Full title
Author / Creator
Riedl, Marc A. , Tachdjian, Raffi , Lumry, William R. , Craig, Timothy , Karakaya, Gül , Gelincik, Asli , Stobiecki, Marcin , Jacobs, Joshua S. , Gokmen, Nihal M. , Reshef, Avner , Gompels, Mark M. , Manning, Michael E. , Bordone, Laura , Newman, Kenneth B. , Treadwell, Sabrina , Wang, Sophie , Yarlas, Aaron , Cohn, Danny M. and OASIS-HAE Team
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
Hereditary angioedema is a rare disorder characterized by episodic, potentially life-threatening swelling caused by kallikrein-kinin dysregulation. Long-term prophylaxis can stabilize this system. Donidalorsen, an antisense oligonucleotide, specifically reduces prekallikrein expression.
In this phase 3, double-blind, randomized trial, we assigne...
Alternative Titles
Full title
Efficacy and Safety of Donidalorsen for Hereditary Angioedema
Authors, Artists and Contributors
Author / Creator
Tachdjian, Raffi
Lumry, William R.
Craig, Timothy
Karakaya, Gül
Gelincik, Asli
Stobiecki, Marcin
Jacobs, Joshua S.
Gokmen, Nihal M.
Reshef, Avner
Gompels, Mark M.
Manning, Michael E.
Bordone, Laura
Newman, Kenneth B.
Treadwell, Sabrina
Wang, Sophie
Yarlas, Aaron
Cohn, Danny M.
OASIS-HAE Team
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_3063464635
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3063464635
Other Identifiers
ISSN
0028-4793,1533-4406
E-ISSN
1533-4406
DOI
10.1056/NEJMoa2402478
